Accurate Estimation of Absolute Dose using EPID Images

EPIDose (US Patent 8,130,905) has a neat history that goes back a ways. In the year 2001, I began a fruitful relationship with Bill and Jeff Simon (Sun Nuclear‘s President/Founder and CEO, respectively) while my friend Paul Jursinic and I were playing around with MapCHECK serial number 1 and publishing our findings. Through the years that followed, I kept in constant contact with Sun Nuclear, as I appreciated their personality of innovation and creativity (and of course their dosimeters). When Canis Lupus LLC launched in August of 2005, I wanted to match the great density and resolution of MV EPID data with the power of their expertise, diode arrays, and analysis tools. Thus was borne EPIDose. It became a staple feature in the Sun Nuclear “Patient QA” product line for over a decade.

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A Few Publications Utilizing or Relevant to EPIDose

Nelms BE, Rasmussen KH, Tome WA. Evaluation of a fast method of EPID-based dosimetry for intensity-modulated radiation therapy. J Appl Clin Med Phys. 2010 Apr 19;11(2):3185.

Nakaguchi Y, Araki F, Kouno T, Ono T, Hioki K. Development of multi-planar dose verification by use of a flat panel EPID for intensity-modulated radiation therapy. Radiol Phys Technol. 2013 Jan;6(1):226-32.

Tatsumi D, Nakada R, Ienaga A, Yomoda A, Inoue M, Ichida T, Hosono M. Electronic portal image device dosimetry for volumetric modulated arc therapy. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2013;69(1):11-8.

Bailey DW, Kumaraswamy L, Bakhtiari M, Malhotra HK, Podgorsak MB. EPID dosimetry for pretreatment quality assurance with two commercial systems. J Appl Clin Med Phys. 2012 Jul 5;13(4):3736.

Varatharaj C, Moretti E, Ravikumar M, Malisan MR, Supe SS, Padovani R. Implementation and validation of a commercial portal dosimetry software for intensity-modulated radiation therapy pre-treatment verification. J Med Phys. 2010 Oct;35(4):189-96.

Bailey DW, Nelms BE, Attwood K, Kumaraswamy L, Podgorsak MB. Statistical variability and confidence intervals for planar dose QA pass rates. Med Phys. 2011 Nov;38(11):6053-64.

Zhen H, Nelms BE, Tome WA. Moving from gamma passing rates to patient DVH-based QA metrics in pretreatment dose QA. Med Phys. 2011 Oct;38(10):5477-89.

Nelms BE, Zhen H, Tomé WA. Per-beam, planar IMRT QA passing rates do not predict clinically relevant patient dose errors. Med Phys. 2011 Feb;38(2):1037-44.

Jursinic PA, Nelms BE. A 2-D diode array and analysis software for verification of intensity modulated radiation therapy delivery. Med Phys. 2003 May;30(5):870-9.